Dr Deepak Jakhar

Exosome TherapyThe Future of Skin Rejuvenation What Are Exosomes? Exosomes are tiny extracellular vesicles — nano-sized messengers released by stem cells. They play a key role in cell-to-cell communication, delivering growth factors, proteins, lipids, and RNA to other cells.In dermatology and cosmetology, exosome therapy is being hailed as a cutting-edge solution for skin rejuvenation, anti-aging, hair restoration, and acne scar repair.Unlike PRP (platelet-rich plasma), which relies on the patient’s own blood components, exosomes are usually derived from stem cells — making them more potent and consistent. How Do Exosomes Work on the Skin? Exosomes work by:Stimulating fibroblasts to produce more collagen and elastinReducing inflammation and oxidative stressPromoting angiogenesis (new blood vessel formation) for better skin healthAccelerating wound healing and post-procedure recoveryThis makes exosome therapy an excellent add-on after procedures like:• Microneedling• Laser resurfacing (fractional CO₂, Erbium, Q-switch)• Radiofrequency treatments• Hair PRP or hair mesotherapy Why Is Exosome Therapy So Popular Right Now? The global dermatology market is buzzing about exosomes because they hit three major beauty trends:Non-invasive treatments: Patients want results without surgery and with minimal downtime. Exosome facials or topical applications fit this need perfectly.Next-gen anti-aging: While Botox and fillers address wrinkles and volume loss, exosomes work at a cellular level to improve skin texture, tone, and resilience.Hair regrowth booster: Exosomes have shown promise in androgenetic alopecia (pattern hair loss) by stimulating dormant hair follicles. What Does the Science Say? Recent clinical studies highlight exosomes’ ability to:• Increase collagen density and dermal thickness• Reduce skin pigmentation and improve evenness• Enhance post-procedure recovery• Improve scalp microcirculation for hair regrowthDermatologists worldwide are incorporating exosomes into their practice, especially for patients with stubborn acne scars or those seeking a non-surgical rejuvenation option. Exosomes vs PRP: Which Is Better? Feature PRP Exosomes Source Patient’s own blood Stem cell-derived Potency Variable, depends on patient Consistent, high potency Use cases Facial rejuvenation, hair regrowth Acne scars, aging skin, hair loss Downtime Mild swelling, bruising Minimal, faster recovery Note: Many clinics now combine PRP + Exosomes for a powerful regenerative combo. What Is an Exosome Facial? An Exosome Facial usually involves:Performing a microneedling session to create controlled micro-injuries.Applying exosome-rich serum topically to penetrate the skin.Allowing 10–15 minutes for absorption and healing.Patients typically notice:Softer, smoother skin within a weekBrighter, more even complexionReduced appearance of fine lines over several sessions Exosomes for Hair Loss Hair clinics are buzzing about exosomes for androgenetic alopecia (male and female pattern baldness). When injected into the scalp:They stimulate dormant hair follicles.They reduce scalp inflammation.They enhance blood supply to follicles.Combined with PRP, mesotherapy, or microneedling, exosome therapy may boost hair density and slow down hair thinning. Are Exosomes Safe? While exosome therapy is generally considered safe, it’s important to:Get treatment at a reputed clinic with qualified dermatologists.Ensure ethical, certified sources of exosomes (avoid unregulated products).Follow post-care instructions carefully.At Dermosphere Clinic, we use top-tier, clinically tested exosome products and tailor treatments to your skin’s specific needs. Who Is an Ideal Candidate? Exosome therapy is suitable for:• People with acne scars or textural irregularities• Those experiencing early signs of aging (fine lines, dullness)• Men and women with mild-to-moderate hair loss• Patients wanting to boost results after microneedling or laserNot sure if you’re a candidate? Schedule a skin analysis at Dermosphere Clinic. Dermosphere’s Expert Insight At Dermosphere, we believe in evidence-based, customized skincare. Exosome therapy isn’t a “one-size-fits-all” — it’s part of a holistic approach combining:Active skincareProfessional proceduresLifestyle adjustmentsWant to explore how exosomes can fit into your regimen? Book a consultation today!  

Trending K-Beauty Clinic TreatmentsWhat’s Hot in 2025? Why Is K-Beauty Still Leading the Global Skincare Game? K-beauty (Korean beauty) isn’t just about cute packaging and 10-step skincare routines — it’s also pioneering advanced clinical treatments that focus on glass skin, pore refinement, hydration, and natural glow.In 2025, dermatology clinics worldwide (including in India) are adopting K-beauty-inspired procedures because they combine:Cutting-edge scienceMinimally invasive techniquesFocus on skin health, not just appearanceLet’s dive into the top trending K-beauty clinical treatments you should know! Skin Botox (Microbotox) What it is: Tiny microdroplets of diluted Botox injected into the superficial skin layer (not deep muscles). Shrinks poresControls oil productionSmoothens fine linesGives a glass-skin, poreless finishAt Dermosphere, we combine Skin Botox with treatments like mesotherapy or microneedling for maximum glow. Salmon DNA (PN/PDRN) Therapy Popularized in Korea as Rejuran Healer, this injectable uses salmon-derived polynucleotides to repair damaged skin, boost collagen, and improve elasticity.Reduces acne scarsHeals sun-damaged skinImproves under-eye textureGives a fresh, youthful glowThis ties into the PN/PDRN injections we covered in yesterday’s blog! Water Shine Injection (Hydro Lifting) Also called Hydro Lift or Hydro Injection, this treatment involves injecting a cocktail of hyaluronic acid, amino acids, vitamins, and minerals into the skin using fine micro-needles.Deep hydration from withinEnhanced skin elasticityRadiant, dewy skinPerfect for patients with dry, dull, or aging skin. Laser Toning (Q-Switch Laser) This Korean laser technique uses low-fluence Q-switch Nd:YAG lasers to:Brighten skin toneReduce pigmentation and frecklesImprove melasmaTighten poresLaser toning is super popular in Asia for achieving the famed K-beauty brightness. Lipolytic Injections (Kybella / Fat Melting Shots) Korean clinics often use lipolytic solutions for small, stubborn fat areas (e.g., double chin, jowls, under-eye fat pads).Non-surgical fat reductionImproved facial contourCombined with HIFU or RF for skin tighteningIn India, these treatments are becoming more common, especially for jawline definition. Exosome Therapy Korean labs were among the first to pioneer exosome-based skin rejuvenation — nano-sized messengers that deliver growth factors and regenerative signals to skin cells.Boosts collagenEnhances post-laser recoveryImproves skin qualityWe covered this in Day 1’s blog, but K-beauty versions often combine exosomes with stem cell extracts for extra power. PDO Thread Lifting Originally popularized in Korea, PDO threads are dissolvable sutures inserted under the skin to lift sagging tissue and stimulate collagen production.Non-surgical faceliftImproved skin textureDefined jawline and cheeksAt Dermosphere, we use Korean PDO and PLLA threads for optimal results. Why Are These Treatments Trending Globally? Natural, subtle enhancement (no overfilled or “plastic” look)Focus on skin quality, not just shapeFast recovery, minimal downtimeCustomizable and combinableK-beauty emphasizes long-term skin health — that’s why even Western celebrities are flying to Seoul or importing these technologies! Dermosphere’s Expert Take We’ve brought these top-tier K-beauty treatments to India, combining them with evidence-based dermatology.Want poreless, glass skin? Try Skin Botox + Laser Toning.Want to heal acne scars? Combine PDRN + microneedling.Want a subtle lift? Go for PDO threads + Skin Botox.Our experts personalize every plan based on your skin’s needs. Patient Love “After Skin Botox, my skin feels so smooth and my makeup applies flawlessly!”“Laser toning has completely evened out my skin tone — no more pigmentation!”“PDO threads gave me a natural lift, and my friends just say I look ‘fresh’.”

Bio-Remodelling Long InjectionsThe Game-Changer in Anti-Aging Dermatology What Is Bio-Remodelling? If you’re familiar with dermal fillers and skin boosters, you might think you know all the injectable options out there. But bio-remodelling is not a filler or a skin booster — it’s a completely new class of anti-aging treatment. Bio-remodelling long injections, like Profhilo, work by stimulating your skin’s own collagen and elastin production rather than adding volume or hydration directly. The result?Firmer, tighter skinSmoother textureRestored elasticity This treatment is sometimes called the “injectable skincare” or “liquid facelift” because it remodels skin from within without changing your facial structure. How Do Bio-Remodelling Injections Work? Bio-remodelling injectables are made of highly concentrated, pure hyaluronic acid (HA) — but here’s the twist: they don’t just hydrate the skin like HA-based skin boosters (such as Restylane Vital or Juvederm Volite).Instead, they use a dual molecular weight HA formula that:Spreads across the skin’s surfaceStimulates fibroblasts to produce more collagen and elastinImproves skin laxity, tone, and firmness over timeUnlike traditional fillers, they don’t sit in one place or add volume — they act as a bio-stimulator, improving the quality of the skin itself. What Areas Can Be Treated? The most popular treatment areas include:• Face (cheeks, jawline, under-eye area)• Neck (to reduce crepey skin)• Décolletage (chest area)• Hands (for rejuvenation)• Arms and knees (for skin tightening in advanced cases) Treatment Schedule Treatment Schedule Bio-remodelling treatments usually follow this protocol:Two sessions spaced 4 weeks apartMaintenance session every 6–12 monthsEach session involves 5 injection points per side of the face, using a special technique called the BAP (Bio Aesthetic Points) method — designed to maximize spread and minimize bruising. Feature Profhilo (Bio-Remodeller) Dermal Fillers Skin Boosters Main purpose Boost collagen & elastin Add volume or reshape Hydrate and plump skin Composition Pure, hybrid HA Cross-linked HA Non-cross-linked HA Placement Superficial spread (BAP points) Targeted areas (cheeks, lips, chin) Broad skin surface Longevity 6–12 months 12–18 months 6–9 months Effect Improves skin quality & firmness Restores contours & volume Hydrates and softens fine lines Why Is Everyone Talking About Bio-Remodelling? Natural ResultsPatients love that bio-remodellers don’t “change” their face — they simply restore skin youthfulness. Minimal DowntimeTiny injections with little to no swelling or bruising mean you can go back to work the same day. Safe and ProvenProducts like Profhilo have undergone rigorous testing and are used in millions of treatments worldwide. Complements Other TreatmentsYou can combine bio-remodelling with Botox, fillers, lasers, or microneedling for comprehensive facial rejuvenation. Who Is an Ideal Candidate? Bio-remodelling is ideal for:• Age 30+ noticing early signs of sagging or dullness• Patients who want skin improvement, not volume• Men and women seeking non-surgical lifting• People concerned about neck wrinkles or “tech neck”• Those looking for a preventive anti-aging boost Results: What to Expect You won’t see overnight miracles. Instead, results develop gradually over 4–8 weeks as your skin produces new collagen. Patients report:Smoother, tighter skinReduced fine linesGlowier, healthier complexionImproved skin texture and elasticity Dermosphere’s Expert Tips At Dermosphere Clinic, we personalize every bio-remodelling plan. Here’s what we advise:Combine Profhilo with microneedling for acne scarsPair with Botox for a smooth + tight lookUse alongside PRP or exosomes for maximum regenerationMaintain with good skincare (retinol, antioxidants, sunscreen) Are There Any Side Effects? Mild redness or tiny bumps at the injection points usually settle within 24–48 hours. Rarely, there can be mild bruising. Make sure you get treated by a qualified dermatologist — precise injection technique is key! Patient Testimonials “My skin feels firmer and more bouncy — like a facelift without surgery.”“I combined Profhilo with Botox, and the results are amazing. Natural but noticeable.”“Finally, a treatment that works on my neck lines!”