Bio-Remodelling Long Injections
The Game-Changer in Anti-Aging Dermatology

What Is Bio-Remodelling?
If you’re familiar with dermal fillers and skin boosters, you might think you know all the injectable options out there. But bio-remodelling is not a filler or a skin booster — it’s a completely new class of anti-aging treatment.
Bio-remodelling long injections, like Profhilo, work by stimulating your skin’s own collagen and elastin production rather than adding volume or hydration directly. The result?
Firmer, tighter skin
Smoother texture
Restored elasticity
This treatment is sometimes called the “injectable skincare” or “liquid facelift” because it remodels skin from within without changing your facial structure.
How Do Bio-Remodelling Injections Work?
Bio-remodelling injectables are made of highly concentrated, pure hyaluronic acid (HA) — but here’s the twist: they don’t just hydrate the skin like HA-based skin boosters (such as Restylane Vital or Juvederm Volite).
Instead, they use a dual molecular weight HA formula that:
Spreads across the skin’s surface
Stimulates fibroblasts to produce more collagen and elastin
Improves skin laxity, tone, and firmness over time
Unlike traditional fillers, they don’t sit in one place or add volume — they act as a bio-stimulator, improving the quality of the skin itself.
What Areas Can Be Treated?
The most popular treatment areas include:
• Face (cheeks, jawline, under-eye area)
• Neck (to reduce crepey skin)
• Décolletage (chest area)
• Hands (for rejuvenation)
• Arms and knees (for skin tightening in advanced cases)
Treatment Schedule
Treatment Schedule
Bio-remodelling treatments usually follow this protocol:
Two sessions spaced 4 weeks apart
Maintenance session every 6–12 months
Each session involves 5 injection points per side of the face, using a special technique called the BAP (Bio Aesthetic Points) method — designed to maximize spread and minimize bruising.
Feature | Profhilo (Bio-Remodeller) | Dermal Fillers | Skin Boosters |
---|---|---|---|
Main purpose | Boost collagen & elastin | Add volume or reshape | Hydrate and plump skin |
Composition | Pure, hybrid HA | Cross-linked HA | Non-cross-linked HA |
Placement | Superficial spread (BAP points) | Targeted areas (cheeks, lips, chin) | Broad skin surface |
Longevity | 6–12 months | 12–18 months | 6–9 months |
Effect | Improves skin quality & firmness | Restores contours & volume | Hydrates and softens fine lines |
Why Is Everyone Talking About Bio-Remodelling?
Natural Results
Patients love that bio-remodellers don’t “change” their face — they simply restore skin youthfulness.
Minimal Downtime
Tiny injections with little to no swelling or bruising mean you can go back to work the same day.
Safe and Proven
Products like Profhilo have undergone rigorous testing and are used in millions of treatments worldwide.
Complements Other Treatments
You can combine bio-remodelling with Botox, fillers, lasers, or microneedling for comprehensive facial rejuvenation.
Who Is an Ideal Candidate?
Bio-remodelling is ideal for:
• Age 30+ noticing early signs of sagging or dullness
• Patients who want skin improvement, not volume
• Men and women seeking non-surgical lifting
• People concerned about neck wrinkles or “tech neck”
• Those looking for a preventive anti-aging boost
Results: What to Expect
You won’t see overnight miracles. Instead, results develop gradually over 4–8 weeks as your skin produces new collagen.
Patients report:
Smoother, tighter skin
Reduced fine lines
Glowier, healthier complexion
Improved skin texture and elasticity
Dermosphere’s Expert Tips
At Dermosphere Clinic, we personalize every bio-remodelling plan. Here’s what we advise:
Combine Profhilo with microneedling for acne scars
Pair with Botox for a smooth + tight look
Use alongside PRP or exosomes for maximum regeneration
Maintain with good skincare (retinol, antioxidants, sunscreen)
Are There Any Side Effects?
Mild redness or tiny bumps at the injection points usually settle within 24–48 hours. Rarely, there can be mild bruising.
Make sure you get treated by a qualified dermatologist — precise injection technique is key!
Patient Testimonials
“My skin feels firmer and more bouncy — like a facelift without surgery.”
“I combined Profhilo with Botox, and the results are amazing. Natural but noticeable.”
“Finally, a treatment that works on my neck lines!”